PARACETAMOL

Paracetamol, also known as acetaminophen and APAP, is a medication used to treat pain and fever.

in India, it is available as Brand Name-

• CALPOL
• CROCIN
• T-98  and other

It is typically used for mild to moderate pain relief.

There is mixed evidence for its use to relieve fever in children.

It is often sold in combination with other medications, such as in many cold medications.

• WINCOLD
• SUMOCOLD
• VODACOF
• HATRIC3 and others

Paracetamol is also used for severe pain, such as cancer pain and pain after surgery, in combination with opioid pain medication.

It is typically used either by mouth or rectally, but is also available by injection into a vein.

Effects last between 2 to 4 hours.

Paracetamol is generally safe at recommended doses.

The recommended maximum daily dose for an adult is 3 or 4 grams.\

Higher doses may lead to toxicity, including liver failure.

Serious skin rashes may rarely occur.

It appears to be safe during pregnancy and when breastfeeding.

In those with liver disease, it may still be used, but in lower doses.

It is classified as a mild analgesic.

It does not have significant anti-inflammatory activity.How it works is not entirely clear.

DETAILS

Formula: C₈H₉NO₂

Molar mass: 151.163 g/mol

Metabolism: Predominantly in the liver

Elimination half-life: 1–4 hours

Metabolites: APAP gluc, APAP sulfate, APAP GSH, APAP cys, NAPQI

IUPAC ID: N-(4-hydroxyphenyl)ethanamide, N-(4-hydroxyphenyl)acetamide

Soluble in: Water, Alcohol

For more details click here- https://en.wikipedia.org/wiki/Paracetamol